Pancreatic Cancer: Some Good (pre-clinical) News

Pancreatic cancer is one of the most aggressive cancers that can hit the body; it’s aggressive enough that studies are even difficult to conduct, which makes new treatment discoveries a very hard task.


Consequently campaigns are being made to increase awareness of the disease, its symptoms and maybe push scientists to work more to find new treatments. Some of the campaigns were even so provocative to the extend of being controversial. One of the latter campaigns is the Pancreatic Cancer Action ad back in 2014, where Pancreatic cancer patient wished they had breast or testicular cancer:

Via DailyMail

(Click on the captioned link for the full video of the campaign)

October 2015 was a good day for pancreatic cancer, where a drug Iriotecan (already in the market) was successfully inserted in a Liposome, which can decrease the side effects and increase the efficacy of the medications (news via FDA). But frankly no major change in the treatment was due just yet.

BUT the good news is that someone is now thinking outside the box! Laura Indolfi a biomedical engineer and her team came up with a new drug delivery system. It basically looks like a patch and it’s now being tested in pre-clinical studies. It can deliver medication directly into the tumour while bypassing all the other organs even the blood, and it is inserted with minimal invasiveness and applied directly on the tumour. The latter, will drastically decrease the side effects, toxicities and definitely will increases the efficacy of the drug.

In her TED Talk (shared below) Indolfi explains why it’s hard to treat pancreatic cancer and how her invention can bypass all those difficulties.

Cheers to such inventions! Cheers to such innovators!

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